The definitive overview of haematology and its recent developments

Haematology has advanced considerably in recent decades. As new developments emerge, there is a continuous need for an accessible and up-to-date survey for medical students, discussing the major haematological disorders, their clinical presentations, their treatments, and more.

Written by specialists with an interest in medical education, Lecture Notes: Haematology is a succinct, highly illustrated student guide to the essentials of this important field. It integrates the physiological, pathological, and clinical dimensions of haematology in a single comprehensive guide, and provides medical students and early-career clinicians with the core knowledge required to succeed in the subject. The 11th edition of this guide includes updated sections and expanded chapters detailing the newest advances in the field.

In this 11th edition of Lecture Notes: Haematology, readers will also find:

• Discussion of both pathogenesis and management of all major haematological disorders
• Online clinical cases with >150 multiple choice questions to allow you to test and apply your knowledge

Lecture Notes: Haematology, 11th edition isa valuable resource for medical students and junior doctors looking to increase their expertise in this medical specialty.

Preface vii

About the companion website ix

1 An introduction to haematopoiesis 1

2 The blood count in health and disease 15

3 Anaemia: general principles 23

4 Haemolytic anaemias 39

5 Disorders of globin synthesis 55

6 An introduction to haematological malignancies 71

7 Cellular and molecular investigations in haematology 79

8 Neoplastic disorders of myeloid cells 91

9 Neoplastic disorders of lymphoid cells 105

10 Plasma cell myeloma and other paraproteinaemias 121

11 Aplastic anaemia and pure red cell aplasia 131

12 Stem cell transplantation and cellular therapy 137

13 Haemostasis and bleeding disorders 147

14 Thrombosis and anticoagulant therapy 163

15 Blood groups and blood transfusion 173

Index 187

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