Acknowledgements vi
1 Thyroid anatomy and physiology 1
2 Hypothyroidism 8
3 Thyrotoxicosis 13
4 Goitre thyroid nodules and cancer 26
5 Adrenal anatomy and physiology 34
6 Adrenal insufficiency 38
7 Primary hyperaldosteronism 47
8 Phaeochromocytomas and paragangliomas 53
9 Congenital adrenal hyperplasia 60
10 Adrenal incidentalomas 66
11 Pituitary anatomy and physiology 69
12 Pituitary tumours and other sellar disorders 74
13 Hypopituitarism 87
14 Hyperprolactinaemia 91
15 Acromegaly 96
16 Cushing syndrome 101
17 Diabetes insipidus 109
18 Hyponatraemia and syndrome of inappropriate antidiuretic hormone secretion 113
19 Male reproductive physiology and hypogonadism 119
20 Gynaecomastia 127
21 Female reproductive physiology amenorrhoea and premature ovarian insufficiency 131
22 Polycystic ovary syndrome 139
23 Menopause 144
24 Calcium homeostasis hypercalcaemia and primary hyperparathyroidism 147
25 Hypocalcaemia 155
26 Osteomalacia 160
27 Osteoporosis 164
28 Paget Disease of Bone 170
29 Disorders of puberty 174
30 Growth and stature 181
31 Endocrine disorders of pregnancy 189
32 Neuroendocrine tumours 198
33 Obesity 209
34 Diabetes mellitus: classification pathogenesis and diagnosis 217
35 Treatment of diabetes mellitus 225
36 Diabetic emergencies 238
37 Diabetic retinopathy 246
38 Diabetic nephropathy 252
39 Diabetic neuropathy 257
40 Musculoskeletal and dermatological manifestations of diabetes 261
Index 269
