ESSENTIAL ENDOCRINOLOGY AND DIABETES

The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details.

Essential Endocrinology and Diabetes provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice.

The text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management.

Essential Endocrinology and Diabetes, Seventh Edition is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science.

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Preface vii

List of abbreviations ix

Part 1: Foundations of Endocrinology 1

1 Overview of endocrinology 3

2 Basic cell biology and hormone synthesis 12

3 Molecular basis of hormone action 22

4 Investigations in endocrinology and diabetes 39

Part 2: Endocrinology – Biology to Clinical Practice 51

5 The hypothalamus and pituitary gland 53

6 The adrenal gland 80

7 Reproductive endocrinology 103

8 The thyroid gland 134

9 Calcium and metabolic bone disorders 155

10 Pancreatic and gastrointestinal endocrinology and endocrine neoplasia 175

Part 3: Diabetes and Obesity 193

11 Overview of diabetes 195

12 Type 1 diabetes 213

13 Type 2 diabetes 239

14 Complications of diabetes 265

15 Obesity 293

Index 311

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